01
Encapsulate
Actives sealed in lipid sphere
Bioactive molecules are enclosed within lipid vesicles composed of natural phospholipids.
- Phospholipid Bilayer
- Encapsulation
- Bioavailability
What is a Liposome?
The Tiny Architecture Behind Liposomal Skincare
Liposomes are microscopic, spherical vesicles made from phospholipid bilayers, similar to the lipid structures found in cell membranes. They encapsulate water- soluble (hydrophilic) and oil-soluble (lipophilic) active ingredients, protecting them and supporting delivery into the skin
LIPOSOME UNDER MICROSCOPE
Transmission electron microscope image showing spherical liposomes.
THE SCIENTIFIC DIFFERENCE
How Liposomal Systems Compare with Conventional Serum
By shielding sensitive actives within biomimetic phospholipid vesicles, liposomal encapsulation prevents premature degradation and enhances cellular uptake compared to conventional delivery
| Parameter | Conventional Delivery | Liposomal Delivery |
|---|---|---|
| Average Size | Macro-molecular actives cannot reach deeper dermal layers | Nanoscale vesicles allow enhanced dermal penetration |
| Skin Absorption | Limited absorption; permeation hindered by the hydrophobic stratum corneum | High absorption via membrane fusion |
| Bioavailability | Low bioavailability (~5-10%) | Up to 4 to 10 times higher cellular uptake |
| Stability | Extremely fragile; rapid degradation into inactive form | Actives shielded from light, oxygen, and metallic ions |
| Release Kinetics | Extremely fragile; rapid degradation into inactive form | Sustained release over 24 h delivery |
| Skin Interaction | High risk of stinging, redness, and inflammatio | Minimal irritation; well-tolerated across sensitive skin |
| Shelf-Life Integrity | Prone to browning, oxidation, and precipitous potency loss | Stable colour and physical integrity across ambient storage |
| Best Suited For | General topical formulations | Liposomal skincare targets skin treatment |
| Efficacy | Marginal dermal impact; mostly superficial exfoliation/hydration | Clinically validated upregulation of procollagen and photo-repair markers |
Conventional Delivery
Macro-molecular actives cannot reach deeper dermal layers
Liposomal Delivery
Nanoscale vesicles allow enhanced dermal penetration
Conventional Delivery
Limited absorption; permeation hindered by the hydrophobic stratum corneum
Liposomal Delivery
High absorption via membrane fusion
Conventional Delivery
Low bioavailability (~5-10%)
Liposomal Delivery
Up to 4 to 10 times higher cellular uptake
Conventional Delivery
Extremely fragile; rapid degradation into inactive form
Liposomal Delivery
Actives shielded from light, oxygen, and metallic ions
Conventional Delivery
Extremely fragile; rapid degradation into inactive form
Liposomal Delivery
Sustained release over 24 h delivery
Conventional Delivery
High risk of stinging, redness, and inflammatio
Liposomal Delivery
Minimal irritation; well-tolerated across sensitive skin
Conventional Delivery
Prone to browning, oxidation, and precipitous potency loss
Liposomal Delivery
Stable colour and physical integrity across ambient storage
Conventional Delivery
General topical formulations
Liposomal Delivery
Liposomal skincare targets skin treatment
Conventional Delivery
Marginal dermal impact; mostly superficial exfoliation/hydration
Liposomal Delivery
Clinically validated upregulation of procollagen and photo-repair markers
What We Observed in Our R&D
A Simple 24-Hour Oxidation Trial
Our R&D team conducted a simple 24-hour oxidation trial using apple slices. We dipped separate apple slices in plain glutathione serum and liposomal glutathione serum for a few seconds, then left them exposed to air for 24 hours. After 24 hours, the slice treated with plain glutathione showed visible browning, while the slice treated with liposomal glutathione serum remained visibly fresher. This visual demonstration shows how liposomal encapsulation stabilises active glutathione, delivering 24 hr antioxidant protection against environmental exposure and free-radical stress
Conventional
With Liposomal Serum
Real Test Results
Actual images from our R&D experiment.
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THE MINDS BEHIND SINORA
Different Expertise. One Scientific Vision
Our breakthroughs in liposomal skincare stem from a combined effort of our dedicated R&D, formulation, and analytical teams, working hand in hand with India’s leading dermatologists and experienced skincare experts. Our scientists synthesise next-generation liposomal formulations developed to protect sensitive actives and deliver unmatched bioavailability. Our pioneering liposomal encapsulation technology and state-of-the-art facility ensure every batch is systematically developed, characterised, and rigorously tested for optimal efficacy. This multidisciplinary scientific mastery ensures our products deliver real, scientifically proven skincare benefits
10% Vitamin C Serum
With Superior Liposomal Technology
Co-created by Dr Snigdha Roy
Exfoliating AHA BHA PHA Serum
With Superior Liposomal Technology
Co-created by Mr. Monjoy Ghosh
Dark Spot Clearing Serum
With Superior Liposomal Technology
Co-created by Mr. Rana Aditya Sankar Das
Bright + Glow 15% Vitamin C Serum
With Superior Liposomal Technology
Co-created by Mr. Suman Banerjee
The Numbers Behind Our Science
Precision You Can Measure
Our liposomal technology is engineered for high encapsulation, optimal particle size and stability – helping skincare actives perform at their best
> 80%
Encapsulation Efficiency (EE)
Ensures more active ingredients are delivered within liposomes
< 300 nm
Particle Size Range
Optimized for better stability and skin interaction.
< 0.30
Polydispersity Index (PDI)
Uniform and consistent particle size distribution for reliable performance
≤ -30 mV
Zeta Potential
Enhanced stability of liposomal vesicles in formulation
24 Months
Stability
Maintains integrity and performance under recommended storage conditions
Liposomal Delivery System
How Liposomal Delivery Works
02
Stabilise
Molecular integrity preserved
The liposome protects sensitive actives against enzymatic breakdown, hydrolysis, and UV degradation. Preserves molecular integrity throughout formulation and storage.
- Stability
- Extended Shelf-Life
- Oxidative Defense
03
PENETRATE
Reaches deep transepidermal layer
The biomimicking liposomes interacts with the skin and passes the stratum corneum barrier. This enables enhanced dermal penetration of actives rather than surface pooling.
- Dermal-Depth Delivery
- Deep penetration
04
Release
Targeted release of the actives
Upon reaching the target sites, liposomal vesicles fuse directly with cell membranes and release the entrapped actives in a controlled manner.
- Membrane Fusion
- Controlled Release
- Intracellular Delivery
05
Perform
Deep cellular rejuvenation
Within cells, the actives upregulate protein synthesis, stimulate cellular turnover, and combat oxidative damage. The result is visibly smoother, firmer, and revitalised skin.
- Skin Revitalisation
- Visible Firming
- Antioxidant Defense
Actives sealed in lipid sphere
Molecular integrity preserved
Reaches deep transepidermal layer
Targeted release of the actives
Deep cellular rejuvenation
Actives sealed in lipid sphere
Molecular integrity preserved
Reaches deep transepidermal layer
Targeted release of the actives
Deep cellular rejuvenation
Have Questions?
Frequently Asked Questions
Learn more about our liposomal technology, ingredients and scientific approach.
A liposome is a microscopic spherical vesicle made from phospholipid bilayers, similar to the skin's natural cell membranes. It can encapsulate active ingredients and help deliver them in a more stable and effective form, supporting better interaction with the skin.
A liposome is a microscopic spherical vesicle made from phospholipid bilayers, similar to the skin's natural cell membranes. It can encapsulate active ingredients and help deliver them in a more stable and effective form, supporting better interaction with the skin.
The primary benefits include deep skin delivery, higher cellular bioavailability, sustained 24-hour active release, reduced ingredient oxidation, and significantly less skin irritation
Yes, because their phospholipid bilayer mimics our cellular membranes, enabling them to interact more with skin cells and deliver actives to dermal cells more effectively than conventional formulations.
SiNORA liposomal products are formulated by encapsulating active ingredients within biocompatible phospholipid bilayers in collaboration with LipoEdgeTM technology. achieving high entrapment efficiency (>80%) and a precise nanoscale vesicle size (<300 nm) for superior stability and absorption.
The skin barrier naturally repels large molecules. Our nanoscale liposomal formulation can easily navigate intercellular pathways, ensuring consistent dermal permeation rather than surface accumulation
Our Products
Something extraordinary is on its way.
Our next generation liposomal skincare collection.
Coming Soon
Our Products
Something extraordinary is on its way.
Coming Soon
Our next generation liposomal skincare collection.
Liposomal Skincare
Engineered Like Science.
Engineered Like Science.
Experienced Like Luxury
Pharmaceutical-grade liposomal delivery meets luxury skincare, protecting active ingredients until the precise moment your skin needs them.
Explore Our Science
Get In Touch
Let's Talk Skin.
Have a question about your skin or the science behind SiNORA?